We investigate how ribosomes and nucleolus regulate gene expression & metabolism and influence development and aging.

Our interdisciplinary approach integrates genetics, genomics, computational and molecular biology.

Below are some of the outstanding questions we are interested in, please click on the titles for more information on the projects:

Interplay Between Nucleolus and Chromatin

Does the nucleolus, the nucleus's central hub, actively contribute to the organization of our genetic material and gene expression?

Ribosome synthesis checkpoint

How do organisms coordinate growth across organs and tissues, and regulate ribosome activity to ensure synchronized growth?

Ribosomes & Metabolism and longevity

Can we more accurately predict protein synthesis by ribosome profiling?

Can we predict cellular metabolism by measuring protein synthesis?

How do ribosomes communicate with cellular metabolic pathways to regulate organism-wide longevity?

OUR MISSION

The Sarinay Cenik Lab is a dynamic, diverse and innovative team of researchers. We are committed to fostering a collaborative and inclusive scientific community that nurtures curiosity, inspires innovation, and drives impactful scientific progress. Our goal is to conduct high-quality, reproducible, innovative and interdisciplinary science that deepen our understanding of biological processes. We believe that training the next generation of scientists is essential. Thus, lab members gain valuable skills and experience in genetics, genomics, computational biology, and molecular biology, preparing them for diverse careers in academia, and biotechnology.